h 1 benzopyran 4 one Search Results


mek inhibitor pd 98059  (Promega)
90
Promega mek inhibitor pd 98059
Mek Inhibitor Pd 98059, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/pd98059/pm31962157-70-14-20
Average 90 stars, based on 1 article reviews
mek inhibitor pd 98059 - by Bioz Stars, 2026-11
90/100 stars
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pymol  (Schrodinger LLC)
90
Schrodinger LLC pymol
Pymol, supplied by Schrodinger LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/pymol/pm33831355-228-14-35
Average 90 stars, based on 1 article reviews
pymol - by Bioz Stars, 2026-11
90/100 stars
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n methylated f moc precursors  (Chem Impex International)
95
Chem Impex International n methylated f moc precursors
N Methylated F Moc Precursors, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/Methyl+hesperidine/pm14707085-54-7-10
Average 95 stars, based on 1 article reviews
n methylated f moc precursors - by Bioz Stars, 2026-11
95/100 stars
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isoquercetin  (Rooibos Ltd)
90
Rooibos Ltd isoquercetin
Isoquercetin, supplied by Rooibos Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/isoquercetin/pm16927447-62-15-9
Average 90 stars, based on 1 article reviews
isoquercetin - by Bioz Stars, 2026-11
90/100 stars
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flavopiridol (alvocidib)  (Adooq Bioscience LLC)
90
Adooq Bioscience LLC flavopiridol (alvocidib)
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Flavopiridol (Alvocidib), supplied by Adooq Bioscience LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/flavopiridol++alvocidib+/pmc04036831-286-8-13
Average 90 stars, based on 1 article reviews
flavopiridol (alvocidib) - by Bioz Stars, 2026-11
90/100 stars
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glycitein (purities ≥ 98%)  (LC Laboratories)
90
LC Laboratories glycitein (purities ≥ 98%)
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Glycitein (Purities ≥ 98%), supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/glycitein/pm29649842-153-3-10
Average 90 stars, based on 1 article reviews
glycitein (purities ≥ 98%) - by Bioz Stars, 2026-11
90/100 stars
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myricetin-3-o-glucoside  (Extrasynthese SA)
90
Extrasynthese SA myricetin-3-o-glucoside
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Myricetin 3 O Glucoside, supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/myricetin+3+o+glucoside/pmc06365461-140-7-15
Average 90 stars, based on 1 article reviews
myricetin-3-o-glucoside - by Bioz Stars, 2026-11
90/100 stars
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myricetin (myr)  (Extrasynthese SA)
90
Extrasynthese SA myricetin (myr)
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Myricetin (Myr), supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/myricetin++myr+/pm37672798-139-24-29
Average 90 stars, based on 1 article reviews
myricetin (myr) - by Bioz Stars, 2026-11
90/100 stars
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pinostrobin  (Extrasynthese SA)
90
Extrasynthese SA pinostrobin
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Pinostrobin, supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/pinostrobin/pm38257349-297-16-25
Average 90 stars, based on 1 article reviews
pinostrobin - by Bioz Stars, 2026-11
90/100 stars
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robinetin  (Extrasynthese SA)
90
Extrasynthese SA robinetin
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Robinetin, supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/robinetin/pmc01951842-113-15-19
Average 90 stars, based on 1 article reviews
robinetin - by Bioz Stars, 2026-11
90/100 stars
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quercetin 3- o -glucoside  (Extrasynthese SA)
90
Extrasynthese SA quercetin 3- o -glucoside
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Quercetin 3 O Glucoside, supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/quercetin+3+o+glucoside/pmc11510656-170-43-50
Average 90 stars, based on 1 article reviews
quercetin 3- o -glucoside - by Bioz Stars, 2026-11
90/100 stars
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quercetin 3- o -rhamnoside  (Extrasynthese SA)
90
Extrasynthese SA quercetin 3- o -rhamnoside
Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with <t>Flavopiridol</t> (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.
Quercetin 3 O Rhamnoside, supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h+1+benzopyran+4+one/quercetin+3+o+rhamnoside/pmc05000740-149-6-23
Average 90 stars, based on 1 article reviews
quercetin 3- o -rhamnoside - by Bioz Stars, 2026-11
90/100 stars
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Image Search Results


Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with Flavopiridol (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.

Journal: Retrovirology

Article Title: HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells

doi: 10.1186/1742-4690-11-30

Figure Lengend Snippet: Tat modulation of ISG requires P-TEFb and Sp1. A . Luciferase activity in THP-Mac lysates expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72, Tat SF2 C25,30,34S or Tat SF2 K28,50A and transfected with IRF7-, MAP2K6-, or MAP2K3-luciferase reporter vectors (the promoter used in the transfected vector is indicated above the bars). Significantly different levels of luciferase activity could be detected between Tat SF2 and Tat SF2 1-72 for all three promoters (MAP2K3: p = 0.04; MAP2K6: p = 0.03; IRF7: p = 0.004, T Test). B . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 , the single exon Tat SF2 1-72 and transfected with MAP2K3-, MAP2K6-, or IRF7-luciferase reporter vectors. “ + Fvp” indicates treatment with Flavopiridol (70 nM). C . Luciferase activity in lysates from THP-Mac expressing the wild-type Tat SF2 or Tat SF2 1-72 and transfected with MAP2K3, MAP2K6-, or IRF7-luciferase reporter vectors in the presence or absence of WP631, a Sp1 inhibitor. “ + WP” indicates treatment with WP631 (0.3 ug/ml). D , E . Western Blot of Tat expressing cells at 8 and 16 h post infection, treated or not treated with Flavopiridol (D) or with WP631 (E) . Dotted lines indicate pairs of values with statistically significant differences.

Article Snippet: For the CDK9 inhibition, cells were treated with Flavopiridol (Alvocidib) at 70 nM (AdooQ.com Biosciences, Irvine, CA).

Techniques: Luciferase, Activity Assay, Expressing, Transfection, Plasmid Preparation, Western Blot, Infection